Welcome to CyMATE - Cytosine Methylation Analysis Tool for Everyone

CyMATE is a web application that allows you to perform a quick and comprehensive methylation analysis of cytosine sites in DNA sequences. CyMATE can handle a set of aligned sequences, i.e. multiple sequence alignment files of the reference sequence ('master') and multiple sample sequences ('clones'). It handles bisulfite-converted samples ('clones') and evaluates the frequency of methylation patterns with respect to a reference sequence ('master'). CyMATE provides for both text and graphical outputs.

For details, please read the  User Guide. For testing purposes, download an example file  here.

If you use results from CyMATE in your published work, please cite:
Hetzl J, Foerster AM, Raidl G, Mittelsten Scheid O (2007) CyMATE: a new tool for methylation analysis of plant genomic DNA after bisulfite sequencing. Plant J 51:526-536.

CyMATE is a joint effort of the  Mittelsten Scheid Group from the GMI and the  Algorithms and Data Structures Group from the Technical University, Vienna.

For questions, reports and comments, contact the author:

Jennifer Hetzl
 jennifer.hetzl(at)gmi.oeaw.ac.at


Acknowledgements:  Austrian Science Fund (FWF),  Net4biz