Control of chromatin fates in pollen
Constitutive heterochromatin is involved in multiple chromosomal processes including silencing of repetitive DNA and chromosome segregation. We have found global centromeric heterochromatin decondensation in Arabidopsis pollen, which evokes a new aspect of constitutive heterochromatin. We aim to isolate genes involved in this process.
Ibarra C, Feng X, Schoft VK, Hsieh TF, Uzawa R, Rodrigues JA, Zemach A, Chumak N, Machlicova A, Nishimura T, Rojas D, Fischer RL, Tamaru H, Zilberman D (2012) Active DNA Demethylation in Plant Companion Cells Reinforces Transposon Methylation in Gametes. Science 337 no.6100:1360-1364.
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Schoft V, et al. (2009) Induction of RNA-directed DNA methylation upon decondensation of constitutive heterochromatin. EMBO Reports 10:1015-1021.