Regulation of root development in Arabidopsis

Our major research focus is to identify regulatory networks that underlie developmental processes of a complex organ, the Arabidopsis root, using a novel approach of combining high throughput confocal microscope imaging of whole roots with genome-wide association studies (GWAS).

Selected publications

Busch W, Moore BT, Martsberger B, Mace DL, Twigg RW, Jung J, Pruteanu-Malinici I, Kennedy SJ, Fricke GK, Clark RL, Ohler U, Benfey PN (2012)  A microfluidic device and computational platform for high-throughput live imaging of gene expression. Nat. Methods online: 30 Sep 2012.

Iyer-Pascuzzi AS, et al. (2011) Cell identity regulators link development and stress responses in the Arabidopsis root. Developmental Cell 21:770-782.

Tsukagoshi H, et al. (2010). Transcriptional regulation of ROS controls transition from proliferation to differentiation in the root. Cell 143:606-616.

Sozzani R, et al. (2010) Spatiotemporal regulation of cell-cycle genes by SHORTROOT links patterning and growth. Nature 466:128-132.

Long TA, et al. (2010) The bHLH transcription factor POPEYE regulates response to iron deficiency in Arabidopsis roots. Plant Cell tpc:110.074096.