Biotrophic fungi colonize living host tissue and are therefore masters in manipulating the immune defense responses, metabolism and development of their host plants. The focus of our research is to elucidate the underlying molecular mechanisms of biotrophy in the model pathosystems Ustilago maydis/Maize and Ustilago bromivora/Brachypodium. In an integrative approach we functionally explore the effectome (pathogen derived secreted manipulative molecules) to gain insights into the targeted host metabolic processes and to understand the critical needs of the pathogens.
Rabe F, Ajami-Rashidi Z, Doehlemann G, et al. (2013) Degradation of the plant defense hormone salicylic acid by the biotrophic fungus Ustilago maydis. Mol Microbiol 89(1):179-88.
Djamei A and Kahmann R (2012). Ustilago maydis: dissecting the molecular interface between pathogen and plant. PLoS Pathog 8(11):e1002955.
Djamei A, Schipper K, Rabe F, et al. (2011) Metabolic priming by a secreted fungal effector. Nature 478(7369):395-8.
Mendoza-Mendoza A, Berndt P, Djamei A, et al. (2009) Physical-chemical plant-derived signals induce differentiation in Ustilago maydis. Mol Microbiol 71(4):895-911.
Djamei A, Pitzschke A, Nakagami H, et al. (2007) Trojan horse strategy in Agrobacterium transformation: abusing MAPK defence signalling. Science 318(5849):453-6.