Frederic Berger

Chromatin architecture and function

The Berger lab is currently recruiting a Master Student

Research focus

More than a simple scaffold for the DNA, the conserved proteins histones participate to regulations of genome activities. We explore how variants of core histones impact on genome expression, organization and inheritance. We also study interactions between histone variants with other chromatin modifications, contributing epigenetic landscapes that modulate cellular events in somatic and reproductive tissues.

Selected Publications

Bowman JL, Kohchi T, Yamato KT et al. (2017) Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome. Cell 171(2):287-304.

Jiang D and Berger F (2017) DNA replication-coupled histone modification maintains Polycomb gene silencing in plants. Science 357(6356):1146-9.

Yelagandula R, Stroud H, Holec S, et al. (2014) The histone variant H2A.W defines heterochromatin and promotes chromatin condensation in Arabidopsis. Cell 158(1): 98-109.

Kawashima T, Maruyama D, Shagirov M, et al. (2014) Dynamic F-actin movement is essential for fertilization in Arabidopsis thaliana. eLife 2014;3:e04501.

Kawashima T, Berger F (2014) Epigenetic reprogramming in plant sexual reproduction. Nat Rev Genet 15(9): 613-24.

Li J, Nie X, Tan JL, Berger F. (2013) Integration of epigenetic and genetic controls of seed size by cytokinin in Arabidopsis. Proc Natl Acad Sci U S A 110(38):15479-84.

Vu TM, Nakamura M, Calarco JP, et al. (2012) RNA-directed DNA methylation regulates parental genomic imprinting at several loci in Arabidopsis. Development 140(14): 2953-60.

Jullien PJ, Susaki D, Yelagandula R, et al. (2012) DNA methylation dynamics during sexual reproduction in Arabidopsis thaliana. Curr Biol 22(19): 1825-30.

Wollmann H, Holec S, Alden K, et al. (2012). Dynamic Deposition of Histone Variant H3.3 Accompanies Developmental Remodeling of the Arabidopsis Transcriptome. PLoS Genetics 8(5):e1002658.

Ingouff M, Rademacher S, Holec S, et al. (2010) Zygotic Resetting of the HISTONE 3 Variant Repertoire Participates in Epigenetic Reprogramming in Arabidopsis. Curr Biol 20(23): 2137-43.

Ingouff M, Hamamura Y, Gourgues, M, et al. (2007) Distinct dynamics of HISTONE3 variants between the two fertilization products in plants. Cur Biol 17(12): 1032-37.

Gregor Mendel Institute of
Molecular Plant Biology GmbH

Dr. Bohr-Gasse 3
1030 Vienna, Austria

T: +43 1 79044-9000
F: +43 1 79044-9001
E: office(at)