Ortrun Mittelsten Scheid

Epigenetic changes in plants

Research focus 

Epigenetic changes contribute significantly to diversity in gene expression and, thereby, to adaptation potential. Using the model plant Arabidopsis, we investigate chromatin, gene expression, recombination, inheritance and natural variation in diploids, upon genome duplication in polyploids and after stress treatments.

Selected Publications

Probst AV, Mittelsten Scheid O (2015) Stress-induced structural changes in plant chromatin. Curr Opin Plant Biol 27:8-16.

Dona M, Mittelsten Scheid O (2015) DNA damage repair in the context of plant chromatin. Plant Physiol 168(4):1206-18.

Baubec T, Finke A, Mittelsten Scheid O, et al. (2014) Meristem-specific expression of epigenetic regulators safeguards transposon silencing in Arabidopsis. EMBO Rep 15(4):446–52.

Cavrak VV, Lettner N, Jamge S, et al. (2014) How a Retrotransposon Exploits the Plant's Heat Stress Response for Its Activation. PLoS Genet 10(1): e1004115.

Rosa M, Von Harder M, Cigliano RA, et al. (2013) The Arabidopsis SWR1 Chromatin-Remodeling Complex Is Important for DNA Repair, Somatic Recombination, and Meiosis. Plant Cell 25(6): 1990-2001.

Förster A, Dinh H, Sedman L, et al. (2011) Genetic rearrangements can modify chromatin features at epialleles. PLoS Genet 7(10):e1002331.

Pecinka A, Fang W, Rehmsmeier M, et al. (2011) Polyploidization increases meiotic recombination frequency in Arabidopsis. BMC Biol 9:24.

Baubec T, Dinh HQ, Pecinka A, et al. (2010) Cooperation of multiple chromatin modifications can generate unanticipated stability of epigenetic states in Arabidopsis. Plant Cell 22(1):34-47.

Förster AM, Hetzl J, Müllner C, et al. (2010) Analysis of bisulfite sequencing data from plant DNA using CyMATE. Methods Mol Biol 631:13-22.

Pecinka A, Dinh HQ, Baubec T, et al. (2010) Epigenetic regulation of repetitive elements is attenuated by prolonged heat stress in Arabidopsis. Plant Cell 22(9):3118-29.

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