One of the most important challenges in biology is to understand how the genotype of an individual gives rise to its phenotype. Using the root as a model system, we want to obtain a systems level understanding of how genotypes determine organ growth and development. Our long-term goals are to understand how, and through which molecular and cellular mechanisms, root growth is quantitatively determined by the genotype. Using this knowledge, we will develop mathematical models with predictive power that accurately capture how the genotype determines root growth in given environments. To accomplish this we use a systems genetics approach, a synthesis from various fields including, genetics, genomics, phenomics, and systems biology.
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